You're contacting media contact of this press release

Title: Investors Take Note as Corbus Pharma Releases Data for ADC Tumor Candidate

New York, New York, United States, 30th Jan 2024 - (Plato Data) - Corbus Pharmaceuticals (NASDAQ:CRBP) jumped on Friday after announcing positive data from a small group of cancer patients who received its antibody-drug conjugate (ADC) CRB-701 in a Phase 1 trial. Citing a December data cut in patients with cancers expressing a tumor-associated antigen called nectin-4, Corbus (CRBP) said that CRB-701 led to an objective response rate (ORR) of 43%, including three partial responses. The data from the first eighteen participants who received the first six dose levels represented the readout, which was part of its Phase 1 dose escalation study for CRB-701 conducted by Corbus’ (CRBP) partner CSPC Pharmaceutical Group (OTCPK:CSPCY) in China.With dosing up to 3.6 mg/kg completed, there were no dose discontinuations or reductions, and most adverse events were grade one or two and reversible, the company said. Dosing is currently underway for the 4.5 mg/kg group, and the company intends to start a U.S. clinical trial for CRB-701 (SYS6002) in Q1 2024.The pharmaceutical landscape has seen a growing interest in antibody-drug conjugates (ADCs), exemplified by recent acquisitions in the industry. Bristol Myers Squibb (Nasdaq: BMY) acquired another ADC, and AbbVie's (Nasdaq: ABBV) proposed $10 billion deal for ImmunoGen's (Nasdaq: IMGN) oncology pipeline reflects this trend. Additionally, Johnson & Johnson's announcement of a $2 billion plan to acquire Ambrx Biopharma (Nasdaq: AMAM)indicates a broader shift towards these drugs as potential advancements in cancer treatment.ADCs, characterized by the linkage of a monoclonal antibody to a small molecule drug with a stable linker, represent a notable advancement in biopharmaceuticals. While primarily developed for cancer treatmen...

This press release is issued by King Newswire