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Title: MtoZ Biolabs’ 4D Proteomics Service Powers High-Throughput, PTM-Aware Research

Boston, MA, United States, 1st May 2025 - 4D proteomics service is an advanced analytical offering designed to push the boundaries of protein characterization through enhanced separation, sensitivity, and speed. Built upon conventional 3D proteomics (retention time, mass-to-charge ratio, and intensity), 4D proteomics introduces ion mobility as a fourth dimension, enabling precise separation of peptide ions based on their collisional cross-section and shape. This concept gained momentum in 2018 with the launch of the Bruker timsTOF Pro system, which integrates Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation–Serial Fragmentation (PASEF) technologies. Together, these innovations significantly improve the detection of low-abundance proteins and the resolution of post-translational modification (PTM) isomers, offering an unparalleled depth of proteomic analysis.To meet the growing demand for high-throughput, modification-aware proteomics from limited sample input, MtoZ Biolabs has launched a dedicated 4D proteomics service powered by the timsTOF Pro platform. Our streamlined workflow translates complex ion mobility data into high-confidence proteomic insights, enabling researchers to explore dynamic proteome changes with exceptional clarity. Whether for biomarker discovery, drug mechanism investigation, systems biology, or clinical metaproteomics, MtoZ Biolabs delivers expert-guided, scalable solutions that accelerate your research with precision and reliability.What Makes 4D Proteomics Different?Beyond adding ion mobility as a fourth analytical dimension, 4D proteomics fundamentally redefines how proteomic data is acquired and interpreted. Unlike conventional workflows that may suffer from peptide co-elution, signal interference, or limited depth, 4D prot...

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